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Hemotology

COMMON APPLICATIONS OF FLOW CYTOMETRY IN HEMATOLOGY

By Dayyal Dg.Twitter Profile | Updated: Monday, 31 July 2017 11:14 UTC
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Principle of working of a flow cytometer
Principle of working of a flow cytometer
  1. Leukemias and lympomas: Immunophenotyping (evaluation of cell surface markers), diagnosis, detection of minimal residual disease, and to identify prognostically important subgroups.
  2. Paroxysmal nocturnal hemoglobinuria: Deficiency of CD 55 and CD 59.
  3. Hematopoietic stem cell transplantation: Enumeration of CD34+ stem cells.
  4. Feto-maternal hemorrhage: Detection and quantitation of foetal hemoglobin in maternal blood sample.
  5. Anemias: Reticulocyte count.
  6. Human immunodeficiency virus infection: For enumeration of CD4+ lymphocytes.
  7. Histocompatibility cross matching.
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