Published in Hemotology
Monday, 17 July 2017 00:46
This is a rapid and simple method, which gives approximate hemoglobin value. It is commonly used for selection of blood donors in blood banks.

A drop of blood is allowed to fall in copper sulphate solution of specific gravity 1.053 from a height of 1 cm. Specific gravity of 1.053 is equivalent to hemoglobin concentration of 12.5 grams/dl. The drop of blood gets covered with copper proteinate and remains discrete for 15-20 seconds. If the drop sinks within this time, its specific gravity is higher than that of copper sulphate solution (i.e. hemoglobin is >12.5 grams/dl) and hemoglobin level is acceptable for donation. If it floats, hemoglobin level is unacceptable. However, specific gravity of whole blood is also affected by total leukocyte count and concentration of plasma proteins. In the presence of leukocytosis (e.g. as in chronic myeloid leukemia) or hypergamma-globulinemia (e.g. multiple myeloma), hemoglobin value will be misleadingly high.

Useful Sites

  • NCBI

    National Center for Biotechnology Information
  • LTO

    Lab Tests Online® by AACC
  • ASCP

    American Society for Clinical Pathology
  • ASM

    American Society for Microbiology
  • The Medical Library®

    Project of BioScience.pk

Connect With Us

Contact Us

All comments and suggestions about this web site are very welcome and a valuable source of information for us. Thanks!

Tel: +(92) 302 970 8985-6

Email: This email address is being protected from spambots. You need JavaScript enabled to view it.

Website: https://www.bioscience.pk

Our Sponsors

The Physio ClubB2BPakistan.com

By using BioScience.pk you agree to our use of cookies to enhance your experience on this website.