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Sabotaging flagella of bacteria to halt infections

Published in Microbiology
Wednesday, 28 September 2016 19:33
Some bacteria have the ability to ‘swim’ in a controlled fashion through the use of appendages called flagella. Researchers think that disabling these flagella is a key step towards infection control.

Motile bacteria move through the function of flagella. These appendages rotate, which propels an organism forwards. This is a little like the propellers on a boat. Some bacteria have one flagellum, others have many, and some possess none at all. Some of the bacteria regarded as human pathogens have flagella. An example of a flagellate bacterium is the ulcer-causing Helicobacter pylori, which uses multiple flagella to propel itself through the mucus lining to reach the stomach epithelium. Some flagella also serve a function in environmental detection, sensing different conditions and signalling to a bacterium to move to or away from a given niche.

Read more: Sabotaging bacteria to halt infections

Interpreting Plates - Colony Morphology

Published in Microbiology
Tuesday, 27 September 2016 17:32
Bacteria grow tremendously fast when supplied with an abundance of nutrients. Different types of bacteria will produce different-looking colonies, some colonies may be colored, some colonies are circular in shape, and others are irregular. The characteristics of a colony (shape, size, pigmentation, etc.) are termed the colony morphology. Colony morphology is a way scientists can identify bacteria. In fact there is a book called Bergey's Manual of Determinative Bacteriology (commonly termed Bergey's Manual) that describes the majority of bacterial species identified by scientists so far.

Although bacterial and fungi colonies have many characteristics and some can be rare, there are a few basic elements that you can identify for all colonies:
  • Form - What is the basic shape of the colony? For example, circular, filamentous, etc.
  • Elevation - What is the cross sectional shape of the colony? Turn the Petri dish on end.
  • Margin - What is the magnified shape of the edge of the colony?
  • Surface - How does the surface of the colony appear? For example, smooth, glistening, rough, dull (opposite of glistening), rugose (wrinkled), etc.
  • Opacity - For example, transparent (clear), opaque, translucent (almost clear, but distorted vision, like looking through frosted glass), iridescent (changing colors in reflected light), etc.
  • Chromogenesis (pigmentation) - For example, white, buff, red, purple, etc.
 

Automated Gram Stainer

Published in Microbiology
Tuesday, 27 September 2016 16:47
These days, your microbiology lab faces increased staffing, time and workflow pressures. Yet you can’t let that influence your quality standards: accuracy, time-to-results and full traceability for accreditation. Automated and designed for intuitive workflow, PREVI® Color Gram gives you confidence in the results you provide. It makes Gram staining easy and safe while ensuring accurate, standardized results in minutes.
 

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